Real suffered their first defeat in the away game against Xacobeo Blu:Sens. Barcelona who crushed Valladolid with 33 points stands on top now, while Valencia and Caja Laboral follow at third and fourth spots.
Results:
| Joventut | 73-77 | Caja Laboral |
| Valencia | 92-74 | Manresa |
| Estudiantes | 77-65 | Granada |
| Bilbao | 70-81 | Unicaja |
| Gran Canaria | 70-77 | Fuenlabrada |
| Cajasol | 99-59 | Murcia |
| Alicante | 100-102 | Bruesa |
| Xacobeo | 78-68 | Real |
| Barcelona | 83-50 | Valladolid |
MVP of round 12 was Tariq Kirksay of Cajasol with an index rating of 30. Erazem Lorbek and Mindaugas Katelynas follwed with 29 each. This week's top three scorers were Louis Bullock with 27, Fernando San Emeterio with 26 and Kostas Vasileiadis with 25. Rafael Hettsheimeir of Xacobeo led all rebounders with 13 and Matt Nielsen of Valencia dished out 7 assists to lead this category.
Standings:
| 1. Barcelona | 11-1 |
| 2. Real | 11-1 |
| 3. Caja Laboral | 9-3 |
| 4. Valencia | 9-3 |
| 5. Cajasol | 7-5 |
| 6. Joventut | 7-5 |
| 7. Bruesa | 6-6 |
| 8. Manresa | 6-6 |
| 9. Unicaja | 5-7 |
| 10. Estudiantes | 5-7 |
| 11. Xacobeo | 5-7 |
| 12. Fuenlabrada | 5-7 |
| 13. Gran Canaria | 4-8 |
| 14. Bilbao | 4-8 |
| 15. Alicante | 4-8 |
| 16. Granada | 4-8 |
| 17. Valladolid | 4-8 |
| 18. Murcia | 2-10 |
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