Baskonia overcame Real Madrid 77-62 in Vitoria as the Liga Endesa resumed after the short Christmas break.
Adam Hanga and Shane Larkin each had 16 points for the winners as Real Madrid drop their third game of the season.
Barcelona were deserved 86-75 road winners over Zaragoza as the Catalan side improved to 11-3.
Valencia kept up the pace at the top of the table as they eased past struggling Manresa 100-55
Bilbao Basket (7-7) 82-85 Real Betis (6-8)
Gran Canaria (9-6) 98-80 Joventut (4-11)
Tenerife (10-4) 89-72 Andorra (8-6)
Murcia (5-9) 100-91 Estudiantes (4-10)
Unicaja (9-5) 87-69 Rio Monbus (4-10)
