Panathinaikos got the better of Barcelona in Athens to increase their unbeaten home run in the EuroLeague to nine games.
Nick Calathes led Panathinaikos with 17 points, 12 assists and five steals as the Greens recorded an 84-75 win.
Maccabi FOX Tel Aviv handed Brose Bamberg its fifth straight loss as the Israeli giants secured a narrow 90-88 win.
Michael Roll led six Maccabi scorers in double figures with a career-high 23 points.
Fenerbahce held Valencia to just seven points in the first quarter but were eventually made to work hard for their 80-67 win.
Kostas Sloukas guided the reigning EuroLeague champions to victory as their good start was erased as the game progressed with Valencia leading for stages.
Sloukas ended with 11 points and 10 assists, while Marko Guduric led Fenerbahce in scoring with 15 points.
CSKA Moscow made light work of Olimpia Milano as a dominating first half, paved the way for a 107-81 win on the road.
Nando De Colo led the winners with 24 points, as CSKA remained top of the standings.