The Toronto Raptors secured a 118-105 victory over the Philadelphia 76ers on Wednesday night in a matchup of depleted rosters.

AJ Lawson led Toronto with 28 points, while Jared Rhoden delivered a career-best performance with 25 points and 12 rebounds.

Orlando Robinson added 25 points and matched his career-high with 12 rebounds as the Raptors (23-43) claimed their fifth win in six games.

Philadelphia (22-43) struggled without eight key players, including Joel Embiid, Tyrese Maxey, Paul George, and Kyle Lowry.

Andre Drummond returned from illness and finished with four points and six rebounds, but the Sixers shot just 7-for-35 from beyond the arc.

Quentin Grimes led Philadelphia with 29 points, and Jeff Dowtin Jr. scored a career-high 20 against his former team.

Toronto took control early, hitting eight three-pointers in a 40-point second quarter, helping them build a 69-55 halftime lead.

Philadelphia cut the deficit to three points by the end of the third, but the Raptors responded with a 12-2 run to start the fourth and never looked back.

Colin Castleton, making his first NBA start, grabbed a career-high 14 rebounds for Toronto.

The Sixers have now lost eight straight road games and dropped five of their last seven overall.

Lonnie Walker IV exited after just 20 seconds following a hard fall and did not return.

The Raptors held a 59-40 rebounding advantage, outscored Philadelphia in the paint 44-34, and shot 40% from three-point range.